3-B]PYRIDIN-3-YL]- - Names and Identifiers
3-B]PYRIDIN-3-YL]- - Physico-chemical Properties
Molecular Formula | C20H13N5O
|
Molar Mass | 339.35 |
Density | 1.42 |
Solubility | 10 mM in DMSO |
pKa | 11.62±0.43(Predicted) |
Storage Condition | -20℃ |
In vitro study | Pim1/AKK1-IN-1 is multi-kinase inhibitor, and hasK d of 380 nM against LKB1 and 53 nM against AAK1. |
3-B]PYRIDIN-3-YL]- - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.947 ml | 14.734 ml | 29.468 ml |
5 mM | 0.589 ml | 2.947 ml | 5.894 ml |
10 mM | 0.295 ml | 1.473 ml | 2.947 ml |
5 mM | 0.059 ml | 0.295 ml | 0.589 ml |
Last Update:2024-01-02 23:10:35
3-B]PYRIDIN-3-YL]- - Reference Information
biological activity | Pim1/AKK1-IN-1 is a potent multi-enzyme inhibitor, can act on Pim1/AKK1/MST2/LKB1,Kd values were 35 nM/53 nM/75 nM/380 nM. |
Target | Kd: 35 nM (Pim1), 53 nM (AKK1), 75 nM (MST2), 380 nM (LKB1) |
in vitro study | Pim1/AKK1-IN-1 is multi-kinase inhibitor, and hasK d of 380 nM against LKB1 and 53 nM against AAK1. |
Last Update:2024-04-09 20:52:54